工业微生物酸胁迫的耐受机制及改造途径

来自 : journals.im.ac.cn/html/cjbcn/2 发布时间：2021-03-26

Abstract: Different types of acids from fermentation environment or industrial microorganisms exist during fermentation process. Acids may inhibit growth and metabolism of industrial strains, namely acid stress. The tolerance mechanisms of acid stress include regulation of intracellular proton concentration, protection and restoration of intracellular macromolecules, changes in cell membrane composition and acid stress response at whole cell level. Screening and modification methods have been applied to improve acid-stress tolerance of industrial strains for decades. In this review, we provide insights into acid-stress tolerance of industrial microorganisms and address the modification of microbial pathways to improve acid-stress tolerance.
2014年10月21日分子外排泵一般由膜外排蛋白、膜融合蛋白 (Membrane fusion protein,MFP) 和外膜通道蛋白 (Outer membrane protein,OMP) 三部分组成[36]。分子外排泵...工业微生物; 酸胁迫; 耐受机制; 改造途径; 菌株改造工业微生物酸胁迫的耐受机制及改造途径